Effect of Intraoperative Dexmedetomidine on Recovery of Gastrointestinal Function After Abdominal Surgery in Older Adults: A Randomized Clinical Trial.

ABSTRACT:

Importance

Postoperative ileus is common after abdominal surgery, and small clinical studies have reported that intraoperative administration of dexmedetomidine may be associated with improvements in postoperative gastrointestinal function. However, findings have been inconsistent and study samples have been small. Further examination of the effects of intraoperative dexmedetomidine on postoperative gastrointestinal function is needed.

Objective

To evaluate the effects of intraoperative intravenous dexmedetomidine vs placebo on postoperative gastrointestinal function among older patients undergoing abdominal surgery.

Design, setting, and participants

This multicenter, double-blind, placebo-controlled randomized clinical trial was conducted at the First Affiliated Hosp

SUBMITTER: Lu Y 

PROVIDER: S-EPMC8517746 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature