Contributions of childhood abuse and neglect to reward neural substrates in adolescence.

ABSTRACT:

Background

Childhood adverse experiences may come to bear particularly during adolescence, when neural reward systems are developing rapidly and psychopathology spikes. Despite prior work differentiating threat- (abuse) vs. deprivation- (neglect) related adversity, no research has yet identified their relative nor interactive contributions to reward neural substrates during adolescence. In the present study, we leveraged a diverse sample of adolescents with different childhood adversity profiles to examine neural responses to reward in relation to varying degrees of abuse vs. neglect.

Methods

Adolescents (N = 45; 23 females; mean age = 14.9 years, SD = 1.9) completed a child-friendly monetary incentive delay task during fMRI acquisition. The self-report Childhood Trauma Ques

SUBMITTER: Yang R 

PROVIDER: S-EPMC8517926 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature