Spontaneous Enhancement of Magnetic Resonance Signals Using a RASER.

ABSTRACT: Nuclear magnetic resonance is usually drastically limited by its intrinsically low sensitivity: Only a few spins contribute to the overall signal. To overcome this limitation, hyperpolarization methods were developed that increase signals several times beyond the normal/thermally polarized signals. The ideal case would be a universal approach that can signal enhance the complete sample of interest in solution to increase detection sensitivity. Here, we introduce a combination of para-hydrogen enhanced magnetic resonance with the phenomenon of the RASER: Large signals of para-hydrogen enhanced molecules interact with the magnetic resonance coil in a way that the signal is spontaneously converted into an in-phase signal. These molecules directly interact with other compounds via dipolar coup

SUBMITTER: Korchak S 

PROVIDER: S-EPMC8518078 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature