Histological and molecular features of the subacromial bursa of rotator cuff tears compared to non-tendon defects: a pilot study.

ABSTRACT:

Background

The role of the subacromial bursa in the development or healing of shoulder pathologies is unclear. Due to this limited knowledge, we aimed to understand specific reactions of the subacromial bursa according to rotator cuff (RC) pathologies compared to non-tendon defects of the shoulder. We hypothesized that the tissue composition and inflammatory status of the bursa are likely to vary between shoulder pathologies depending on the presence and the extent of RC lesion.

Method

Bursa samples from patients with either 1) shoulder instability with intact RC (healthy bursa, control), 2) osteochondral pathology with intact RC, 3) partial supraspinatus (SSP) tendon tear, or 4) full-thickness SSP tear were investigated histologically and on gene expression level.

Result

SUBMITTER: Minkwitz S 

PROVIDER: S-EPMC8518155 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature