Placebo effects in low back pain: A systematic review and meta-analysis of the literature.

ABSTRACT:

Background and objective

The current treatments of primary musculoskeletal low back pain (LBP) have a low to moderate efficacy, which might be improved by looking at the contribution of placebo effects. However, the size of true placebo effects in LBP is unknown. Therefore, a systematic review and meta-analysis were executed of randomized controlled trials investigating placebo effects in LBP.

Databases and data treatment

The study protocol was registered in the international prospective register of systematic reviews Prospero (CRD42019148745). A literature search (in PubMed, Embase, The Cochrane Library, CINAHL and PsycINFO) up to 2021 February 16th yielded 2,423 studies. Two independent reviewers assessed eligibility and risk of bias.

Results

Eighteen studies were e

SUBMITTER: van Lennep JHPA 

PROVIDER: S-EPMC8518410 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature