The levonorgestrel intrauterine system versus endometrial ablation for heavy menstrual bleeding: a cost-effectiveness analysis.

ABSTRACT:

Objective

To evaluate the costs and non-inferiority of a strategy starting with the levonorgestrel intrauterine system (LNG-IUS) compared with endometrial ablation (EA) in the treatment of heavy menstrual bleeding (HMB).

Design

Cost-effectiveness analysis from a societal perspective alongside a multicentre randomised non-inferiority trial.

Setting

General practices and gynaecology departments in the Netherlands.

Population

In all, 270 women with HMB, aged ≥34 years old, without intracavitary pathology or wish for a future child.

Methods

Randomisation to a strategy starting with the LNG-IUS (n = 132) or EA (n = 138). The incremental cost-effectiveness ratio was estimated.

Main outcome measures

Direct medical costs and (in)direct non-medical costs w

SUBMITTER: van den Brink MJ 

PROVIDER: S-EPMC8518490 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature