Development of a versatile copper-responsive gene expression system in the plant-pathogenic fungus Fusarium graminearum.

ABSTRACT: Fusarium graminearum is an important plant-pathogenic fungus that causes Fusarium head blight on wheat and barley, and ear rot on maize worldwide. This fungus has been widely used as a model organism to study various biological processes of plant-pathogenic fungi because of its amenability to genetic manipulation and well-established outcross system. Gene deletion and overexpression/constitutive expression of target genes are tools widely used to investigate the molecular mechanism underlying fungal development, virulence, and secondary metabolite production. However, for fine-tuning gene expression and studying essential genes, a conditional gene expression system is necessary that enables repression or induction of gene expression by modifying external conditions. Until now, only a few c

SUBMITTER: Kim S 

PROVIDER: S-EPMC8518565 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature