Temporal changes in cause-specific death in men with localised prostate cancer treated with radical prostatectomy: a population-based, nationwide study.

ABSTRACT:

Background and objective

Changes in diagnostic work-up, histopathological assessment, and treatment of men with prostate cancer during the last 20 years have affected the prognosis. The objective was to investigate the risk of prostate cancer death in men with clinically localised prostate cancer treated with radical prostatectomy in Sweden in 2000-2010.

Methods

Population-based, nationwide, study on men with clinically localised prostate cancer treated with radical prostatectomy in the period 2000-2010. Cox regression analyses were used to assess differences in risk of prostate cancer death according to calendar period for diagnosis and stratified on risk category.

Results

The study included 19 330 men with a median follow-up of 12.4 years. Men diagnosed in 2007-2008

SUBMITTER: Thomsen FB 

PROVIDER: S-EPMC8518635 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature