Bithiophene-Cored, mono-, bis-, and tris-(Trimethylammonium)-Substituted, bis-Triarylborane Chromophores: Effect of the Number and Position of Charges on Cell Imaging and DNA/RNA Sensing.

ABSTRACT: The synthesis, photophysical, and electrochemical properties of selectively mono-, bis- and tris-dimethylamino- and trimethylammonium-substituted bis-triarylborane bithiophene chromophores are presented along with the water solubility and singlet oxygen sensitizing efficiency of the cationic compounds Cat¹⁺ , Cat²⁺ , Cat(i)²⁺ , and Cat³⁺ . Comparison with the mono-triarylboranes reveals the large influence of the bridging unit on the properties of the bis-triarylboranes, especially those of the cationic compounds. Based on these preliminary investigations, the interactions of Cat¹⁺ , Cat²⁺ , Cat(i)²⁺ , and Cat³⁺ with DNA, RNA, and DNApore were investigated in buffered solutions. The same compounds were

SUBMITTER: Berger SM 

PROVIDER: S-EPMC8518794 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature