Feasibility of Velocity-Selective Arterial Spin Labeling in Breast Cancer Patients for Noncontrast-Enhanced Perfusion Imaging.

ABSTRACT:

Background

Dynamic contrast-enhanced (DCE) MRI is the most sensitive method for detection of breast cancer. However, due to high costs and retention of intravenously injected gadolinium-based contrast agent, screening with DCE-MRI is only recommended for patients who are at high risk for developing breast cancer. Thus, a noncontrast-enhanced alternative to DCE is desirable.

Purpose

To investigate whether velocity selective arterial spin labeling (VS-ASL) can be used to identify increased perfusion and vascularity within breast lesions compared to surrounding tissue.

Study type

Prospective.

Population

Eight breast cancer patients.

Field strength/sequence

A 3 T; VS-ASL with multislice single-shot gradient-echo echo-planar-imaging readout.

Assessment

SUBMITTER: Franklin SL 

PROVIDER: S-EPMC8518819 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature