The connectome predicts resting-state functional connectivity across the Drosophila brain.

ABSTRACT: Anatomical connectivity can constrain both a neural circuit's function and its underlying computation. This principle has been demonstrated for many small, defined neural circuits. For example, connectome reconstructions have informed models for direction selectivity in the vertebrate retina^1,2 as well as the Drosophila visual system.³ In these cases, the circuit in question is relatively compact, well-defined, and has known functions. However, how the connectome constrains global properties of large-scale networks, across multiple brain regions or the entire brain, is incompletely understood. As the availability of partial or complete connectomes expands to more systems and species^4-8 it becomes critical to understand how this detaile

SUBMITTER: Turner MH 

PROVIDER: S-EPMC8519013 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature