Evaporation-Induced Self-Assembly of Small Peptide-Conjugated Silica Nanoparticles.

ABSTRACT: Self-assembly processes guide disordered molecules or particles into long-range organized structures due to specific supramolecular interactions among the building entities. Herein, we report a unique evaporation-induced self-assembly (EISA) strategy for four different silica nanoparticle systems obtained through peptide functionalization of the particle surface. First, covalent peptide-silica coupling was investigated in detail, starting with the grafting of a single amino acid (L-serine) and expanded to specific small peptides (up to four amino acids) and transferred to different particle types (MCM-48-type MSNs, solid nanoparticles, and newly developed virus-like nanoparticles). These materials were investigated regarding their ability to undergo EISA, which was shown to be independent

SUBMITTER: von Baeckmann C 

PROVIDER: S-EPMC8519068 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature