A novel tool for improving the interpretation of isotope bone scans in metastatic prostate cancer.

ABSTRACT:

Objectives

The isotope bone scan (IBS) is the gold-standard imaging modality for detecting skeletal metastases as part of prostate cancer staging. However, its clinical utility for assessing skeletal metastatic burden is limited due to the need for subjective interpretation. We designed and tested a novel custom software tool, the Metastatic Bone Scan Tool (MetsBST), aimed at improving interpretation of IBSs, and compared its performance with that of an established software programme.

Methods

We used IBS images from 62 patients diagnosed with prostate cancer and suspected bone metastases to design and implement MetsBST in MATLAB by defining thresholds used to identify the texture and size of metastatic bone lesions. The results of MetsBST were compared with those of the comm

SUBMITTER: Alshehri AHD 

PROVIDER: S-EPMC8519658 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature