Prenatal PM_2.5 affects atopic dermatitis depending on maternal anxiety and gender: COCOA study.

ABSTRACT:

Background

The prevalence of atopic dermatitis (AD) is increasing worldwide. Prenatal particulate matter with an aerodynamic diameter <2.5 μm (PM_2.5) and maternal anxiety during pregnancy has been suggested as a potential causes of AD. This study investigated the effects of prenatal PM_2.5 and maternal anxiety on AD and identified the critical period of PM_2.5 exposure for AD in infants.

Methods

This study included 802 children from the COCOA birth cohort study with follow-up data at 1 year of age. PM_2.5 was estimated by land-use regression models and prenatal anxiety was measured with a questionnaire. AD was diagnosed by doctor at 1 year of age. Logistic regression analysis and Bayesian distributed lag interaction models were applie

SUBMITTER: Kim S 

PROVIDER: S-EPMC8519998 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature