A Prospective, Multicenter, Single-Blind, Randomized, Controlled Study of VYC-15L, a Hyaluronic Acid Filler, in Adults for Correction of Infraorbital Hollowing.

ABSTRACT:

Background

Rejuvenation of the under-eye area is a popular facial aesthetic treatment option.

Objectives

This study evaluated the safety and effectiveness of VYC-15L for the correction of moderate or severe infraorbital hollowing.

Methods

This was a randomized, controlled, single-blind study with a primary endpoint defined as the proportion of participants with ≥1-grade improvement at Month 3 assessed by an evaluating investigator employing the Allergan Infraorbital Hollow Scale. Three-dimensional imaging was conducted to assess infraorbital volume up to Month 12. Procedure pain and injection-site responses (ISRs) were documented, and safety was monitored throughout the study.

Results

At Month 3, the difference between treatment (83.1%) and control (15.6%) was

SUBMITTER: Fabi S 

PROVIDER: S-EPMC8520027 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature