'Pee'BuSt Trial: A single-centre prospective randomized study comparing functional and anatomic outcomes after augmentation  urethroplasty with penile skin graft versus buccal mucosa graft for anterior urethral stricture disease.

ABSTRACT:

Purpose

To assess the surgical outcomes of augmentation urethroplasty (AU) using penile skin graft (PSG) compared to buccal mucosa graft (BMG) in anterior urethral stricture disease.

Method

Between January 2018 and January 2019, 100 patients with anterior urethral stricture planned for AU were randomized into PSG or BMG arms (CTRI/2018/07/015028). Anatomic and functional variables were compared pre-operatively and post-operatively. Primary outcome was success rate at 18 months and it was defined if any of the three criteria were met, i.e. either maximum urinary flow (Qmax) > 15 ml/s or urethral calibration of 16 French or ability to traverse the repair with 17 French cystoscope. Secondary outcomes were functional parameters such as International Prostate Symptom Score (IPSS)

SUBMITTER: Tyagi S 

PROVIDER: S-EPMC8520101 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature