The role of oxidative stress in patients with recurrent pregnancy loss: a review.

ABSTRACT:

Background

Recurrent pregnancy loss (RPL) presents one of the main problems in the field of reproductive medicine, due to the unknown etiology in 50% of cases, as well as limited evidence-based diagnostic and therapeutic modalities. Recent studies indicate that systemic and placental oxidative stress (OS) represents an essential factor in the etiopathogenesis of RPL. This article is a comprehensive narrative synthesis of previously published studies concerning the role of oxidative stress in the etiology of recurrent pregnancy loss.

Methods

We conducted literature search of published studies in the English language focusing on oxidative stress and its association with recurrent pregnancy loss (RPL) utilizing the Medline and Cochrane databases from 2000 through January 2021.

SUBMITTER: Zejnullahu VA 

PROVIDER: S-EPMC8520213 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature