Intraoperative serosal extracellular mapping of the human distal colon: a feasibility study.

ABSTRACT:

Background

Cyclic motor patterns (CMP) are the predominant motor pattern in the distal colon, and are important in both health and disease. Their origin, mechanism and relation to bioelectrical slow-waves remain incompletely understood. During abdominal surgery, an increase in the CMP occurs in the distal colon. This study aimed to evaluate the feasibility of detecting propagating slow waves and spike waves in the distal human colon through intraoperative, high-resolution (HR), serosal electrical mapping.

Methods

HR electrical recordings were obtained from the distal colon using validated flexible PCB arrays (6 × 16 electrodes; 4 mm inter-electrode spacing; 2.4 cm², 0.3 mm diameter) for up to 15 min. Passive unipolar signals were obtained and analysed.

Results<

SUBMITTER: Lin AY 

PROVIDER: S-EPMC8520224 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature