Whole genome sequence of a non-toxigenic Corynebacterium diphtheriae strain from a hospital in southeastern China.

ABSTRACT:

Background

Sporadic cases of infection with non-toxigenic Corynebacterium diphtheriae (C. diphtheriae) isolates have been reported in regions covered by the Diphtheria-Tetanus-Pertussis vaccine, but no information describing the whole genome of non-toxigenic strains collected in China is available. Therefore, in this work, the complete genome of a non-toxigenic strain of C. diphtheriae from a hospital located in southeastern China was performed.

Results

This non-toxigenic isolate belonged to the belfanti biotype and possessed a unique ST (assigned as ST799 in pubMLST). ErmX was present in the genome sequence and this isolate owned the resistance to erythromycin and clindamycin. Genes coding for virulence factors involved in adherence, iron-uptake and regulation of diphtheria

SUBMITTER: Li G 

PROVIDER: S-EPMC8520229 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature