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Visit-to-visit fasting blood glucose variability and lifetime risk of cardiovascular disease: a prospective study.


ABSTRACT:

Aims

Previous studies suggested an adverse association between higher fasting blood glucose (FBG) variability and cardiovascular disease (CVD). Lifetime risk provides an absolute risk assessment during the remainder of an individual's life. However, the association between FBG variability and the lifetime risk of CVD is uncertain.

Objective

We aimed to investigate the effect of the visit-to-visit FBG variability on the lifetime risk of CVD.

Methods

This study included participants from the Kailuan Study who did not have CVD at index ages 35, 45, and 55 years. The FBG variability was defined as the coefficient of variation (CV) of three FBG values that were measured during the examination periods of 2006-2007, 2008-2009, and 2010-2011. We used a modified Kaplan-Merrier

SUBMITTER: Bi J 

PROVIDER: S-EPMC8520235 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature