Frequency and Characterization of Movement Disorders in Anti-IgLON5 Disease.

ABSTRACT:

Background and objectives

Anti-IgLON5 disease is a recently described neurologic disease that shares features of autoimmunity and neurodegeneration. Abnormal movements appear to be frequent and important but have not been characterized and are underreported. We describe the frequency and types of movement disorders in a series of consecutive patients with this disease.

Methods

In this retrospective, observational study, the presence and phenomenology of movement disorders were assessed with a standardized clinical questionnaire. Available videos were centrally reviewed by 3 experts in movement disorders.

Results

Seventy-two patients were included. In 41 (57%), the main reason for initial consultation was difficulty walking along with one or several concurrent movement

SUBMITTER: Gaig C 

PROVIDER: S-EPMC8520389 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature