Dual energy window imaging for optimisation of P/V ratios in VP SPECT.

ABSTRACT:

Purpose

Ventilation-perfusion single-photon emission computed tomography (VP SPECT) plays an important role in pulmonary embolism diagnosis. Rapid results may be obtained using same-day ventilation followed by perfusion imaging, but generally requires careful attention to achieving an optimal count rate ratio (P/V ratio) of ≥ 3:1. This study investigated whether the ratio of counts simultaneously acquired in adjacent primary and Compton scatter energy windows (E_ratio) on V SPECT was predictive of final normalised perfusion count rate (PCR_norm) on P SPECT using [^99mTc]Tc-macroaggregated albumin (MAA), thus allowing for optimisation of P/V ratios.

Methods

Same-day VP SPECT studies acquired using standard protocols in adult patients during a 2-y

SUBMITTER: Doruyter AGG 

PROVIDER: S-EPMC8520548 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature