Association of remnant cholesterol with nonalcoholic fatty liver disease: a general population-based study.

ABSTRACT:

Background

Remnant cholesterol (RC) mediates the progression of coronary artery disease, diabetic complications, hypertension, and chronic kidney disease. Limited information is available on the association of RC with nonalcoholic fatty liver disease (NAFLD). This study aimed to explore whether RC can be used to independently evaluate the risk of NAFLD in the general population and to analyze the predictive value of RC for NAFLD.

Methods

The study included 14,251 subjects enrolled in a health screening program. NAFLD was diagnosed by ultrasound, and the association of RC with NAFLD was assessed using the receiver operating characteristic (ROC) curve and logistic regression equation.

Results

Subjects with elevated RC had a significantly higher risk of developing NAFLD

SUBMITTER: Zou Y 

PROVIDER: S-EPMC8520640 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature