Course of postoperative relapse in non-small cell lung cancer is strongly associated with post-progression survival.

ABSTRACT:

Background

For early-stage non-small cell lung cancer (NSCLC), surgical resection is considered the most effective treatment strategy and curative treatment. Unfortunately, even after complete resection, almost half of all patients with stage I-IIIA NSCLC relapse and die. Although the possibility of a cure for postoperative recurrence of NSCLC is significantly low, the course of subsequent treatment can possibly affect overall survival (OS). Here, we examined the association of relapse-free survival (RFS) and post-progression survival (PPS) with OS in patients with postoperative recurrence of NSCLC.

Methods

We evaluated 128 patients with NSCLC who underwent complete resection between January 2007 and December 2018. The association between RFS and PPS on OS was examined at th

SUBMITTER: Imai H 

PROVIDER: S-EPMC8520813 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature