Resource allocation for different types of vaccines against COVID-19: Tradeoffs and synergies between efficacy and reach.

ABSTRACT:

Objective

Vaccine shortage and supply-chain challenges have caused limited access by many resource-limited countries during the COVID-19 pandemic. One of the primary decisions for a vaccine-ordering decision-maker is how to allocate the limited resources between different types of vaccines effectively. We studied the tradeoff between efficacy and reach of the two vaccine types that become available at different times.

Methods

We extended a Susceptible-Infected-Recovered-Deceased (SIR-D) model with vaccination, ran extensive simulations with different settings, and compared the level of infection attack rate (IAR) under different reach ratios between two vaccine types under different resource allocation decisions.

Results

We found that when there were limited resources

SUBMITTER: Kim D 

PROVIDER: S-EPMC8520874 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature