Whole-exome sequencing for high-risk primary prostatic extra-gastrointestinal stromal tumor: A case report.

ABSTRACT: The low incidence rates of prostatic extra-gastrointestinal stromal tumors (EGIST), combined with the lack of published guidelines on its treatment, often results in its misdiagnosis and challenges in the treatment of patients, even in cases with high-risk factors. The present case study reported a 65-years-old Chinese male patient, who presented with intermittent hematuria and lower urinary tract symptoms for three months. The colonoscopy results revealed no gastrointestinal lesions; however, a core biopsy diagnosed an EGIST, which subsequently underwent radical prostatocystotomy, standard pelvic lymph node resection, and bricker ileal conduit diversion. The postoperative pathological results suggested a high-risk primary prostatic EGIST, according to the aggressive behavior of the GIST.

SUBMITTER: Lu L 

PROVIDER: S-EPMC8521387 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature