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Index Admission and Thirty-Day Readmission Outcomes of Patients With Cancer Presenting With STEMI.


ABSTRACT:

Background

National-level data of cancer patients' readmissions after ST-segment elevation myocardial infarction (STEMI) are lacking.

Objectives

The primary aim of this study was to compare the rates and causes of 30-day readmissions in patients with and without cancer.

Methods

Among patients admitted with STEMI in the United States National Readmission Database (NRD) from October 2015-December 2017, we identified patients with the diagnosis of active breast, colorectal, lung, or prostate cancer. The primary endpoint was the 30-day unplanned readmission rate. Secondary endpoints included in-hospital outcomes during the index admission and causes of readmissions. A propensity score model was used to compare the outcomes of patients with and without cancer.

Results

A total of 385,522 patients were included in the analysis: 5956 with cancer and 379,566 without cancer. After propensity score matching, 23,880 patients were compared (Cancer = 5949, No Cancer = 17,931). Patients with cancer had higher 30-day readmission rates (19% vs. 14%, p < 0.01). The most common causes for readmission among patients with cancer were cardiac (31%), infectious (21%), oncologic (17%), respiratory (4%), stroke (4%), and renal (3%). During the first readmission, patients with cancer had higher adjusted rates of in-hospital mortality (15% vs. 7%; p < 0.01) and bleeding complications (31% vs. 21%; p < 0.01), compared to the non-cancer group. In addition, cancer (OR 1.5, 95% CI 1.2-1.6, p < 0.01) was an independent predictor for 30-day readmission.

Conclusions

About one in five cancer patients presenting with STEMI will be readmitted within 30 days. Cardiac causes predominated the reason for 30-day readmissions in patients with cancer.

SUBMITTER: Osman M 

PROVIDER: S-EPMC8521583 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature

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Publications

Index Admission and Thirty-Day Readmission Outcomes of Patients With Cancer Presenting With STEMI.

Osman Mohammed M   Benjamin Mina M MM   Balla Sudarshan S   Kheiri Babikir B   Bianco Christopher C   Sengupta Partho P PP   Daggubati Ramesh R   Malla Midhun M   Liu Stephen V SV   Mamas Mamas M   Patel Brijesh B  

Cardiovascular revascularization medicine : including molecular interventions 20210416


<h4>Background</h4>National-level data of cancer patients' readmissions after ST-segment elevation myocardial infarction (STEMI) are lacking.<h4>Objectives</h4>The primary aim of this study was to compare the rates and causes of 30-day readmissions in patients with and without cancer.<h4>Methods</h4>Among patients admitted with STEMI in the United States National Readmission Database (NRD) from October 2015-December 2017, we identified patients with the diagnosis of active breast, colorectal, lu  ...[more]

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