Xpert Ultra Assay on Stool to Diagnose Pulmonary Tuberculosis in Children.

ABSTRACT:

Background

The World Health Organization recommends the Xpert MTB/RIF Ultra assay for diagnosing pulmonary tuberculosis (PTB) in children. Though stool is a potential alternative to respiratory specimens among children, the diagnostic performance of Xpert Ultra on stool is unknown. Thus, we assessed the diagnostic performance of Xpert Ultra on stool to diagnose PTB in children.

Methods

We conducted a cross-sectional study among consecutively recruited children (< 15 years of age) with presumptive PTB admitted in 4 tertiary care hospitals in Dhaka, Bangladesh, between January 2018 and April 2019. Single induced sputum and stool specimens were subjected to culture, Xpert, and Xpert Ultra. We considered children as bacteriologically confirmed on induced sputum if any test perfo

SUBMITTER: Kabir S 

PROVIDER: S-EPMC8521743 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature