Functional glyco-metagenomics elucidates the role of glycan-related genes in environments.

ABSTRACT:

Background

Glycan-related genes play a fundamental role in various processes for energy acquisition and homeostasis maintenance while adapting to the environment in which the organism exists; however, their role in the microbiome in the environment is unclear.

Methods

Sequence alignment was performed between known glycan-related genes and complete genomes of microorganisms, and optimal parameters for identifying glycan-related genes were determined based on the alignments. Using the constructed scheme (> 90% of identity and > 25 aa of alignment length), glycan-related genes in various environments were identified from 198 different metagenome data.

Results

As a result, we identified 86.73 million glycan-related genes from the metagenome data. Among the 12 environments

SUBMITTER: Takihara H 

PROVIDER: S-EPMC8522060 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature