Prognostic value of immune-related lncRNA pairs in patients with bladder cancer.

ABSTRACT:

Background

The characteristics of immune-related long non-coding ribonucleic acids (ir-lncRNAs), regardless of their specific levels, have important implications for the prognosis of patients with bladder cancer.

Methods

Based on The Cancer Genome Atlas database, original transcript data were analyzed. The ir-lncRNAs were obtained using a coexpression method, and their differentially expressed pairs (DE-ir-lncRNAs) were identified by univariate analysis. The lncRNA pairs were verified using a Lasso regression test. Thereafter, receiver operating characteristic curves were generated, and an optimal risk model was established. The clinical value of the model was verified through the analysis of patient survival rates, clinicopathological characteristics, presence of tumor-infi

SUBMITTER: Gao Z 

PROVIDER: S-EPMC8522197 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature