Design and reporting characteristics of clinical trials investigating sedation practices in the paediatric intensive care unit: a scoping review by SCEPTER (Sedation Consortium on Endpoints and Procedures for Treatment, Education and Research).

ABSTRACT:

Objectives

To conduct a scoping review of sedation clinical trials in the paediatric intensive care setting and summarise key methodological elements.

Design

Scoping review.

Data sources

PubMed, Embase, Cumulative Index to Nursing and Allied Health Literature and grey references including ClinicalTrials.gov from database inception to 3 August 2021.

Study selection

All human trials in the English language related to sedation in paediatric critically ill patients were included. After title and abstract screening, full-text review was performed. 29 trials were eligible for final analysis.

Data extraction

A coding manual was developed and pretested. Trial characteristics were double extracted.

Results

The majority of trials were single centre (22/29,

SUBMITTER: Lee JJ 

PROVIDER: S-EPMC8522672 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature