Considerations for designing and implementing combination HIV cure trials: findings from a qualitative in-depth interview study in the United States.

ABSTRACT:

Background

An increasing number of HIV cure trials involve combining multiple potentially curative interventions. Until now, considerations for designing and implementing complex combination HIV cure trials have not been thoroughly considered.

Methods

We used a purposive method to select key informants for our study. Informants included biomedical HIV cure researchers, regulators, policy makers, bioethicists, and community members. We used in-depth interviews to generate ethical and practical considerations to guide the design and implementation of combination HIV cure research. We analyzed the qualitative data using conventional content analysis focused on inductive reasoning.

Results

We interviewed 11 biomedical researchers, 4 community members, 2 regulators, 1 poli

SUBMITTER: Dube K 

PROVIDER: S-EPMC8522863 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature