Timely surveillance and temporal calibration of disease response against human infectious diseases.

ABSTRACT:

Background

Disease surveillance and response are critical components of epidemic preparedness. The disease response, in most cases, is a set of reactive measures that follow the outcomes of the disease surveillance. Hence, timely surveillance is a prerequisite for an effective response.

Methodology/principal findings

We apply epidemiological soundness criteria in combination with the Latent Influence Point Process and time-to-event models to construct a disease spread network. The network implicitly quantifies the fertility (whether a case leads to secondary cases) and reproduction (number of secondary cases per infectious case) of the cases as well as the size and generations (of the infection chain) of the outbreaks. We test our approach by applying it to historic dengue c

SUBMITTER: Najeebullah K 

PROVIDER: S-EPMC8523075 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature