Drug-eluting beads TACE is safe and non-inferior to conventional TACE in HCC patients with TIPS.

ABSTRACT:

Objectives

This study aims to compare the safety and effectiveness between transarterial chemoembolization (TACE) with drug-eluting beads (DEB-TACE) and conventional TACE (cTACE) using lipiodol-based regimens in HCC patients with a transjugular intrahepatic portosystemic shunt (TIPS).

Methods

This retrospective study included patients with patent TIPS who underwent TACE from January 2013 to January 2019 that received either DEB-TACE (DEB-TACE group, n = 57) or cTACE (cTACE group, n = 62). The complications, liver toxicity, overall survival (OS), time to progression (TTP), and objective response rate (ORR) were compared between the groups.

Results

Altogether, 119 patients (50 ± 11 years, 107 men) were evaluated. The incidence of adverse events, including abdominal pain

SUBMITTER: Fan W 

PROVIDER: S-EPMC8523393 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature