Dialyzer surface area is a significant predictor of mortality in patients on hemodialysis: a 3-year nationwide cohort study.

ABSTRACT: A target Kt/V of > 1.4 and use of a high-flux dialyzer are recommended for patients on hemodialysis. However, there is little information on the relationship between the dialyzer surface area and mortality in these patients. In this nationwide cohort study, we aimed to clarify this relationship by analyzing data from the Japanese Society for Dialysis Therapy for 2010-2013. We enrolled 234,638 patients on hemodialysis who were divided according to quartile for dialyzer surface area into the S group (small, < 1.5 m²), M group (medium, 1.5 m²), L group (large, 1.6 to < 2.0 m²), or XL group (extra-large, ≥ 2.0 m²). We assessed the association of each group with 3-year mortality using Cox proportional hazards models and performed propensity score matc

SUBMITTER: Abe M 

PROVIDER: S-EPMC8523692 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature