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Multiple osteolytic primary peripheral T-cell bone lymphoma: the first case report.

ABSTRACT: Peripheral T-cell lymphoma accounts for about 10% of all cases of non-Hodgkin's lymphoma. However, less than 5% of patients with non-Hodgkin's lymphoma present with hypercalcaemia as the initial symptom, and less than 1% present with primary bone lesions. We herein describe a 76-year-old Chinese man who was diagnosed with primary bone adult T-cell lymphoma with extensive osteolysis, including bone loss in the radius, as the initial manifestation. He had developed severe generalised bone pain and an inability to raise his arms. X-ray examination revealed osteolytic destruction of the forearm with loss of the radial diaphysis. The patient was diagnosed with peripheral T-cell lymphoma based on his immunohistochemical results. He began treatment with the CHOPE chemotherapy regimen, which resulted in significant improvement of his bone pain.

SUBMITTER: Li C 

PROVIDER: S-EPMC8524712 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature

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Multiple osteolytic primary peripheral T-cell bone lymphoma: the first case report.

Li Chen C   Wang Weiguo W   Xu Lingyun L   Zheng Dingyun D   Zhang Miao M   Zhang Qin Q   Wu Xiaoqian X   Yao Yue Y   Huang Wenyue W   Li Xue X   Ying Peipei P   Wang Xiuxiu X   Shang Liu L   Feng Yuhu Y  

The Journal of international medical research 20211001 10

Peripheral T-cell lymphoma accounts for about 10% of all cases of non-Hodgkin's lymphoma. However, less than 5% of patients with non-Hodgkin's lymphoma present with hypercalcaemia as the initial symptom, and less than 1% present with primary bone lesions. We herein describe a 76-year-old Chinese man who was diagnosed with primary bone adult T-cell lymphoma with extensive osteolysis, including bone loss in the radius, as the initial manifestation. He had developed severe generalised bone pain and  ...[more]