A brief history and popularity of methods and tools used to estimate micro-evolutionary forces.

ABSTRACT: Population genetics is a field of research that predates the current generations of sequencing technology. Those approaches, that were established before massively parallel sequencing methods, have been adapted to these new marker systems (in some cases involving the development of new methods) that allow genome-wide estimates of the four major micro-evolutionary forces-mutation, gene flow, genetic drift, and selection. Nevertheless, classic population genetic markers are still commonly used and a plethora of analysis methods and programs is available for these and high-throughput sequencing (HTS) data. These methods employ various and diverse theoretical and statistical frameworks, to varying degrees of success, to estimate similar evolutionary parameters making it difficult to get a conc

SUBMITTER: Kidner J 

PROVIDER: S-EPMC8525119 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature