Impact of portal hypertension on short- and long-term outcomes after liver resection for intrahepatic cholangiocarcinoma: A propensity score matching analysis.

ABSTRACT:

Objective

We explored the impact of clinically significant portal hypertension (CSPH) on short- and long-term outcomes of intrahepatic cholangiocarcinoma (ICC) after liver resection (LR).

Methods

Data of 352 ICC patients with cirrhosis who underwent LR were extracted from the Primary Liver Cancer Big Data (PLCBD) between 2005 and 2015 and reviewed. A nomogram based on logistic analyses was developed to illustrate the influencing factors of post-hepatectomy liver failure (PHLF). The impact of CSPH on long-term survival was explored through propensity score matching (PSM) analysis, log-rank test, Cox proportional hazards model, and Kaplan-Meier curves.

Results

A total of 106 patients had CSPH, and 246 patients did not. A nomogram established based on GGT level, CSPH, in

SUBMITTER: Fu J 

PROVIDER: S-EPMC8525133 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature