FreeSurfer based cortical mapping and T1-relaxometry with MPnRAGE: Test-retest reliability with and without retrospective motion correction.

ABSTRACT: A test-retest study of FreeSurfer derived cortical thickness, cortical surface area, and cortical volume, as well as quantitative R1 relaxometry assessed on the midpoint of the cortex, was performed on a cohort of pediatric subjects (6-12 years old) scanned without sedation using SNARE-MPnRAGE (self navigated retrospective motion corrected magnetization prepared with n rapid gradient echoes) imaging. Reliability was assessed with coefficients of variation (CoVs) and intraclass correlation coefficients (ICCs) and statistical tests were used to determine differences with and without SNARE motion correction. Comparison of the test-retest measures of SNARE-MPnRAGE with prospectively motion corrected PROMO MPRAGE were also performed. When SNARE motion correction was used all parameters had stat

SUBMITTER: Kecskemeti S 

PROVIDER: S-EPMC8525331 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature