A Previously Undescribed Highly Prevalent Phage Identified in a Danish Enteric Virome Catalog.

ABSTRACT: Gut viruses are important, yet often neglected, players in the complex human gut microbial ecosystem. Recently, the number of human gut virome studies has been increasing; however, we are still only scratching the surface of the immense viral diversity. In this study, 254 virus-enriched fecal metagenomes from 204 Danish subjects were used to generate the Danish Enteric Virome Catalog (DEVoC) containing 12,986 nonredundant viral scaffolds, of which the majority was previously undescribed, encoding 190,029 viral genes. The DEVoC was used to compare 91 healthy DEVoC gut viromes from children, adolescents, and adults that were used to create the DEVoC. Gut viromes of healthy Danish subjects were dominated by phages. While most phage genomes (PGs) only occurre

SUBMITTER: Van Espen L 

PROVIDER: S-EPMC8525569 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature