Retinal OFF-Pathway Overstimulation Leads to Greater Accommodation-Induced Choroidal Thinning.

ABSTRACT:

Purpose

To examine the interactions between accommodation and overstimulation of the retinal ON- and OFF-pathways, and their association with changes in choroidal thickness (ChT) and vascularity.

Methods

Optical coherence tomography imaging of the choroid of twenty young adults (ages 25 ± 5 years) was performed before and after a series of 30-minute-long viewing tasks, including reading a bright text on dark background (ON-pathway overstimulation) and dark text on bright background (OFF-pathway overstimulation), and a control task of viewing a movie with unbiased ON-/OFF-pathway activation. The viewing tasks were performed with relaxed, and 5 diopter (D) accommodation (induced by soft contact lenses) demands. Both reading texts were matched for the mean luminance (35 cd/m2),

SUBMITTER: Hoseini-Yazdi H 

PROVIDER: S-EPMC8525845 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature