Comparing Continuous and Binary Group-based Trajectory Modeling Using Statin Medication Adherence Data.

ABSTRACT:

Background

Of 58 medication adherence group-based trajectory modeling (GBTM) published studies, 74% used binary and 26% used continuous GBTM. Few studies provided a rationale for this choice. No medication adherence studies have compared continuous and binary GBTM.

Objective

The objective of this study was to assess whether continuous versus binary GBTM: (1) impacts adherence trajectory shapes; and (2) results in the differential classification of patients into adherence groups.

Methods

Patients were prevalent statin users with myocardial infarction hospitalization, 66+ years old, and continuously enrolled in fee-for-service Medicare. Statin medication adherence was measured 6 months prehospitalization using administrative claims. Final GBTM specifications beyond defa

SUBMITTER: Hickson RP 

PROVIDER: S-EPMC8525904 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature