Systematic review and meta-analysis of risk scores in prediction for the clinical outcomes in patients with acute variceal bleeding.

ABSTRACT:

Background

Acute variceal bleeding (AVB) is a life-threatening condition that needs risk stratification to guide clinical treatment. Which risk system could reflect the prognosis more accurately remains controversial. We aimed to conduct a meta-analysis of the predictive value of GBS, AIMS65, Rockall (clinical Rockall score and full Rockall score), CTP and MELD.

Method

PubMed, Web of Science, Embase, Cochrane library, WANGFANG and CNKI were searched. Twenty-eight articles were included in the study. The Meta-DiSc software and MedCalc software were used to pool the predictive accuracy.

Results

Concerning in-hospital mortality, CTP, AIMS65, MELD, Full-Rockall and GBS had a pooled AUC of 0.824, 0.793, 0.788, 0.75 and 0.683, respectively. CTP had the highest sensitivity o

SUBMITTER: Yang L 

PROVIDER: S-EPMC8525940 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature