Depressive rumination is correlated with brain responses during self-related processing.

ABSTRACT:

Background

Rumination, a tendency to focus on negative self-related thoughts, is a central symptom of depression. Studying the self-related aspect of such symptoms is challenging because of the need to distinguish self effects from the emotional content of task stimuli. This study employed an emotionally neutral self-related paradigm to investigate possible altered self-processing in depression and its link to rumination.

Methods

People with major depressive disorder (n = 25) and controls (n = 25) underwent task-based electro-encephalogram recording. We studied late event-related potentials, along with low-frequency oscillatory power. We compared electroencephalogram metrics between groups and correlated them with depressive symptoms and reported rumination.

SUBMITTER: Hsu TY 

PROVIDER: S-EPMC8526127 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature