Hippocampal gamma rhythms during Y-maze navigation in the juvenile rat.

ABSTRACT: The neurobiology of postnatal hippocampal development in rodents is receiving increased attention as a means to address neurodevelopmental questions and to better understand the neural code(s) for spatial navigation in adulthood. We previously showed that spontaneous alternation (SA) in a Y-maze, which emerges at the end of the third postnatal week, was related to changes in fast glutamatergic synaptic transmission. In adults, oscillations in the hippocampal local field potential (LFP) (i.e., theta, 4-12 Hz; slow gamma, 25-55 Hz; and fast gamma, 65-100 Hz) have been shown to coordinate the activity of spatially tuned cell types in the hippocampus during route planning and execution. Other investigators have shown that theta activity matures during the first month of life. However, relation

SUBMITTER: McHail DG 

PROVIDER: S-EPMC8526138 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature