Early angiographic signs of retinopathy of prematurity requiring treatment.

ABSTRACT:

Background/objectives

Fluorescein angiography (FA) has been a pivotal tool to study the pathophysiology of retinopathy of prematurity (ROP) in vivo. We examined the course of ROP using FA in order to assess the predictive value of angiographic features.

Subjects/methods

This is an observational retrospective cohort multi-center study of eyes screened for ROP with binocular indirect ophthalmoscope and with FA. All infants undergoing screening examination for ROP who had retinal vasculature limited to Zone I and posterior Zone II vascularization underwent FA between 31 and 34 weeks postmenstrual age. RetCam fundus imaging and video digital fluorescein angiography were performed in the neonatal intensive care units. Masked grading of the FA images was retrospectively conducted

SUBMITTER: Lepore D 

PROVIDER: S-EPMC8526581 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature