Defining focal brain stimulation targets for PTSD using neuroimaging.

ABSTRACT:

Introduction

Focal brain stimulation has potential as a treatment for posttraumatic stress disorder (PTSD). In this review, we aim to inform selection of focal brain stimulation targets for treating PTSD by examining studies of the functional neuroanatomy of PTSD and treatment response. We first briefly review data on brain stimulation interventions for PTSD. Although published data suggest good efficacy overall, the neurobiological rationale for each stimulation target is not always clear.

Methods

Therefore, we assess pre- and post-treatment (predominantly psychotherapy) functional neuroimaging studies in PTSD to determine which brain changes seem critical to treatment response. Results of these studies are presented within a previously proposed functional neural systems mo

SUBMITTER: van Rooij SJH 

PROVIDER: S-EPMC8526638 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature