Behavioral, Anatomical and Heritable Convergence of Affect and Cognition in Superior Frontal Cortex.

ABSTRACT: Cognitive abilities and affective experience are key human traits that are interrelated in behavior and brain. Individual variation of cognitive and affective traits, as well as brain structure, has been shown to partly underlie genetic effects. However, to what extent affect and cognition have a shared genetic relationship with local brain structure is incompletely understood. Here we studied phenotypic and genetic correlations of cognitive and affective traits in behavior and brain structure (cortical thickness, surface area and subcortical volumes) in the pedigree-based Human Connectome Project sample (N = 1091). Both cognitive and affective trait scores were highly heritable and showed significant phenotypic correlation on the behavioral level. Cortical thickness in the left superior f

SUBMITTER: Kraljevic N 

PROVIDER: S-EPMC8526801 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature