Presentation and survival by hormonal receptor status in metaplastic breast cancer: A propensity score-matched analysis.

ABSTRACT:

Background

Metaplastic breast cancer (MBC) is a rare and aggressive form of breast cancer. The effectiveness of chemotherapy (CT) for MBC remains controversial. The present study aimed to evaluate the efficacy of CT combined hormone receptor (HR) status on MBC patients with high risk (T1-4N2-3M0 and T4N0-1M0) by propensity-score matching (PSM).

Methods

A retrospective study was performed to analyze MBC from the SEER database. Breast cancer-specific survival (BCSS) was analyzed using the Kaplan-Meier curve. Cox proportional hazard models were used to assess BCSS. PSM was used to make 1:1 case-control matching.

Results

This study identified 3116 patients. The median follow-up time was 44 months (range, 1-321 months). About 62.5 % of patients received CT. 23.0 % of patie

SUBMITTER: Wang S 

PROVIDER: S-EPMC8527051 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature