Intraosseous Injections Are Safe And Effective in Knee Osteoarthritis: A Systematic Review.

ABSTRACT:

Purpose

To evaluate clinical outcomes after intraosseous injection for knee osteoarthritis systematically with available clinical evidence.

Methods

A systematic search methodology of the PUBMED, EMBASE, and CINAHL databases was conducted in November 2020. The search workflow was in adherence to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The following inclusion criteria were adopted: clinical trials of any level of evidence, reporting clinical outcomes following intraosseous injections of bone substitutes or biologic agents, and mesenchymal stem cells or platelet-rich plasma into the knee as treatment modalities for osteoarthritis. Duplicate data and articles not written in English were excluded from this review.

Results

Six studie

SUBMITTER: Betzler BK 

PROVIDER: S-EPMC8527247 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature